Deputed as a case worker after a failed mission in Paris, Alice (Noomi Rapace) - a hard-hitting CIA operative - is called back into action by her mentor Eric Lasch (Academy Award winner Michael Douglas). On her trust-no-one mission to save London from biological terrorism, Alice is faced with life-threatening perils and is on a run for her life. Lured into a ruse, Alice turns to ex-soldier Jack (Orlando Bloom) to prevent the lethal biological attack on London.

Unlocked also stars John Malkovich and Toni Colete. The film is directed by Michael Apted and produced by Lorenzo di Bonaventura, Georgina Townsley, Erik Howsam and Claudia Bluemhuber.